Dolutegravir Impurities

Dolutegravir propyl analouge

CAS No. : NA
Synonyms : (4R)-N-(2,4-difluorobenzyl)-4-methyl-6,8-dioxo-7-propoxy-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-a]pyrido[1,2-d]pyrazine-9-carboxamide
Catalog No. : SA20202
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Dolutegravir isopropyl analouge

CAS No. : NA
Synonyms : Dolutegravir -isopropylether impurity; (4R)-N-(2,4-difluorobenzyl)-7-isopropoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-a]pyrido[1,2-d]pyrazine-9 carboxamide; (4R,12aS)-N-(2,4-difluorobenzyl)-7-isopropoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-a]pyrido[1,2-d]pyrazine-9-carboxamide
Catalog No. : SA20201
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2-[(1E)-2-Phenylethenyl]-3-(phenylmethoxy)-4H-pyran-4-one

CAS No. : 1206102-05-7
Synonyms : (E)-3-(benzyloxy)-2-styryl-4H-pyran-4-one
Catalog No. : SA20227
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4-Oxo-4H-pyran-2,5-dicarboxylic Acid 2,5-Diethyl Ester

CAS No. : 1246616-74-9
Synonyms : 4-Oxo-4H-pyran-2,5-dicarboxylic Acid 2,5-Diethyl Ester
Catalog No. : SA20226
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4-Oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic Acid

CAS No. : 119736-16-2
Synonyms : 3-Benzyloxy-4-oxo-4H-pyran-2-carboxylic Acid; 4-Oxo-3-(phenylmethoxy)-4H-pyran-2-carboxylic Acid
Catalog No. : SA20225
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(R)-2-(4-Hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-7-carboxylic Acid

CAS No. : NA
Synonyms : (R)-2-(4-Hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-7-carboxylic Acid
Catalog No. : SA20224
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(4R,12As)-7-Hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2h-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid

CAS No. : 1246616-73-8
Synonyms : (4R,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
Catalog No. : SA20223
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1-(2,2-Dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester

CAS No. : 1246616-75-0
Synonyms : diethyl 1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate
Catalog No. : SA20222
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1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid

CAS No. : 1206102-06-8
Synonyms : 1-(2,3-Dihydroxypropyl)-1,4-dihydro-4-oxo-3-(phenylmethoxy)-2-pyridinecarboxylic Acid
Catalog No. : SA20221
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1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid Methyl Ester

CAS No. : 1206102-07-9
Synonyms : 1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid Methyl Ester; Methyl 1-(2,3-dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylate; Methyl 3-(benzyloxy)-1-(2,3-dihydroxypropyl)-4-oxo-1,4-dihydropyridine-2-carboxylate
Catalog No. : SA20220
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(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

CAS No. : 1206102-11-5
Synonyms : (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalog No. : SA20219
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(R)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-2,3,4,8-tetrahydro-1H-pyrido[1,2-a]pyrazine-7-carboxamide

CAS No. : NA
Synonyms : (R)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-2,3,4,8-tetrahydro-1H-pyrido[1,2-a]pyrazine-7-carboxamide; Dolutegravir impurity E
Catalog No. : SA20218
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Diethyl 3-Bromo-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2,5-dicarboxylate

CAS No. : 1246616-77-2
Synonyms : 3-Bromo-1,4-dihydro-4-oxo-1-(2-oxoethyl)-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester
Catalog No. : SA20217
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3-Bromo-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester

CAS No. : 1246616-76-1
Synonyms : Diethyl 3-Bromo-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate
Catalog No. : SA20216
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(4R,12aS)-7-Bromo-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid Ethyl Ester

CAS No. : 1246616-78-3
Synonyms : (4R,12aS)-7-Bromo-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid Ethyl Ester
Catalog No. : SA20215
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3-Benzyloxy-2-(2-hydroxy-2-phenylethyl)-4H-pyran-4-one

CAS No. : 1206102-04-6
Synonyms : 3-(Benzyloxy)-2-(2-hydroxy-2-phenylethyl)-4-oxo-4H-pyran; 2-(2-Hydroxy-2-phenylethyl)-3-(phenylmethoxy)-4H-pyran-4-one
Catalog No. : SA20214
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(4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid

CAS No. : NA
Synonyms : (4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid
Catalog No. : SA20213
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4-Desfluoro-6-fluoro Dolutegravir

CAS No. : 2244161-72-4
Synonyms : 2,6-Difluoro Dolutegravir; (4R,12aS)-N-(2,6-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Dolutegravir impurity C
Catalog No. : SA20212
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Desdifluoro Dolutegravir

CAS No. : NA
Synonyms : Benzylamine Dolutegravir; (4R,12aS)-N-benzyl-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Dolutegravir impurity B
Catalog No. : SA20211
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4-Defluoro Dolutegravir

CAS No. : 1863916-87-3
Synonyms : 2-Fluoro Dolutegravir; (4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; (4R,12aS)-N-[(2-Fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalog No. : SA20210
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2-Defluoro Dolutegravir

CAS No. : 1863916-88-4
Synonyms : 4-Fluoro Dolutegravir; (4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalog No. : SA20209
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Dolutegravir SR Isomer

CAS No. : 1309560-49-3
Synonyms : 4S,12aR Enantiomer; (4S,12aR)-N-(2,4-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalog No. : SA20208
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Dolutegravir RR Isomer

CAS No. : 1357289-29-2
Synonyms : 4R, 12aR Diastereomer; (4R,12aR)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pPyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalog No. : SA20207
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Dolutegravir Sodium Salt

CAS No. : 1051375-19-9
Synonyms : Dolutegravir sodium; sodium (4R,12aS)-9-(2,4-difluorobenzylcarbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-a]pyrido[1,2-d]pyrazin-7-olate; N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide sodium salt
Catalog No. : SA20206
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Dolutegravir O-Methyl Enantiomer Impurity

CAS No. : NA
Synonyms : (4S,12aR)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalog No. : SA20205
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Dolutegravir O-Methyl 12-Epi Impurity

CAS No. : NA
Synonyms : (4R,12aR)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Catalog No. : SA20204
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Dolutegravir

CAS No. : 1051375-16-6
Synonyms : (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Tivicay
Catalog No. : SA20203
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Dolutegravir Impurities

Dolutegravir propyl analouge

Dolutegravir isopropyl analouge

2-[(1E)-2-Phenylethenyl]-3-(phenylmethoxy)-4H-pyran-4-one

4-Oxo-4H-pyran-2,5-dicarboxylic Acid 2,5-Diethyl Ester

4-Oxo-3-[(phenylmethyl)oxy]-4H-pyran-2-carboxylic Acid

(R)-2-(4-Hydroxybutan-2-yl)-9-methoxy-1,8-dioxo-2,8-dihydro-1H-pyrido[1,2-a]pyrazine-7-carboxylic Acid

(4R,12As)-7-Hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2h-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid

1-(2,2-Dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester

1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid

1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid Methyl Ester

(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethoxy)-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

(R)-N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-2,3,4,8-tetrahydro-1H-pyrido[1,2-a]pyrazine-7-carboxamide

Diethyl 3-Bromo-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-2,5-dicarboxylate

3-Bromo-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester

(4R,12aS)-7-Bromo-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid Ethyl Ester

3-Benzyloxy-2-(2-hydroxy-2-phenylethyl)-4H-pyran-4-one

(4S,12aS)-3,4,6,8,12,12a-Hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic Acid

4-Desfluoro-6-fluoro Dolutegravir

Desdifluoro Dolutegravir

4-Defluoro Dolutegravir

2-Defluoro Dolutegravir

Dolutegravir SR Isomer

Dolutegravir RR Isomer

Dolutegravir Sodium Salt

Dolutegravir O-Methyl Enantiomer Impurity

Dolutegravir O-Methyl 12-Epi Impurity

Dolutegravir