Sapropterin is a cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU). Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase. Synthink is a most trusted source of Sapropterin Degradation Impurity, Sapropterin Genotoxic impurity, Sapropterin Process Impurity, USP related compound, Sapropterin Nitrosamine impurity, N-Nitroso impurity etc. which are listed on this page.