tert-Butyl 8-Oxo-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
Price : $395 – $1,455
CAS No. | : 877402-44-3 |
Mol F. | : C11H13F3N4O3 |
Mol W. | : 306.24 |
Cat No. | : SA10433 |
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Description
Product Name | tert-Butyl 8-Oxo-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate |
Synonyms | 5,6-Dihydro-8-oxo-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-carboxylic Acid 1,1-Dimethylethyl Ester |
Related API | Sitagliptin |
Category | Impurities |
tert-Butyl 8-Oxo-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate product with CAS: 877402-44-3 is also known as 5,6-Dihydro-8-oxo-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-carboxylic Acid 1,1-Dimethylethyl Ester. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. tert-Butyl 8-Oxo-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate is generally used for Quality Control (QC), Quality Assurance (QA) during commercial production of Sitagliptin and its related formulations. Moreover, 5,6-Dihydro-8-oxo-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-7(8H)-carboxylic Acid 1,1-Dimethylethyl Ester is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.
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