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Sofosbuvir 3′,5′-Bis-O-Phosphoramidate

(2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate;

Sofosbuvir-35-Bis-O-Phosphoramidate

Specifications:

CAS No.

: 1337482-17-3

Mol F.

: C34H45FN4O13P2

Mol W.

: 798.69

Cat No.

: SA15407

Appearance

Pack Size Price Availability
10 mg $195 In Stock
25 mg $295 In Stock
50 mg $555 In Stock
100 mg $995 In Stock
250 mg $1995 In Stock
Custom Please Enquire

Product Name

: Sofosbuvir 3′,5′-Bis-O-Phosphoramidate

CAS No.

: 1337482-17-3

Mol F.

: C34H45FN4O13P2

Mol W.

: 798.69

Cat No.

: SA15407

Appearance

Synonyms

: (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate;

Related API

: Sofosbuvir

Category

Sofosbuvir 3′,5′-Bis-O-Phosphoramidate product with CAS: 1337482-17-3 is also known as (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. It is used in Sofosbuvir impurity profiling as per limits and threshold values specified by respective drug legislation, FDA, and pharmacopoeial guidelines. Moreover, (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.

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