Sofosbuvir 3′-O-Phosphoramidate; Sofosbuvir impurity G
Price : $455 – $2,555
| CAS No. | : 1337482-15-1 |
| Mol F. | : C22H29FN3O9P |
| Mol W. | : 529.45 |
| Cat No. | : SA15408 |
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Description
| Product Name | Sofosbuvir 3′-O-Phosphoramidate |
| Synonyms | (2S)-isopropyl 2-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yloxy)(phenoxy)phosphorylamino)propanoate |
| Related API | Sofosbuvir |
| Category | Impurities |
Sofosbuvir 3′-O-Phosphoramidate product with CAS: 1337482-15-1 is also known as (2S)-isopropyl 2-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yloxy)(phenoxy)phosphorylamino)propanoate. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. It is used in Sofosbuvir impurity profiling as per limits and threshold values specified by respective drug legislation, FDA, and pharmacopoeial guidelines. Moreover, (2S)-isopropyl 2-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yloxy)(phenoxy)phosphorylamino)propanoate is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.
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