RP-isomer of sofosbuvir; Sofosbuvir (R)-Phosphate; PSI-7976
Price : $595 – $3,295
| CAS No. | : 1190308-01-0 |
| Mol F. | : C22H29FN3O9P |
| Mol W. | : 529.46 |
| Cat No. | : SA15405 |
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Description
| Product Name | RP-isomer of sofosbuvir; Sofosbuvir (R)-Phosphate |
| Synonyms | (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate |
| Related API | Sofosbuvir |
| Category | Impurities |
RP-isomer of sofosbuvir; Sofosbuvir (R)-Phosphate product with CAS: 1190308-01-0 is also known as (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. It is used in Sofosbuvir impurity profiling as per limits and threshold values specified by respective drug legislation, FDA, and pharmacopoeial guidelines. Moreover, (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.
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