3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one
| CAS No. | : 877402-45-4 |
| Mol F. | : C6H5F3N4O |
| Mol W. | : 206.13 |
| Cat No. | : SA10439 |
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Description
| Product Name | 3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one |
| Synonyms | 6,7-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-8(5H)-one |
| Related API | Sitagliptin |
| Category | Impurities |
3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one product with CAS: 877402-45-4 is also known as 6,7-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-8(5H)-one. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. 3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one is generally used for Quality Control (QC), Quality Assurance (QA) during commercial production of Sitagliptin and its related formulations. Moreover, 6,7-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-8(5H)-one is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.
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