2′-Alkene Sofosbuvir; 2’-Defluro-2’-methylene Sofosbuvir; 2-ALKENE SOFOSBUVIR
Price : $795 – $3,555
| CAS No. | : 2095551-20-3 |
| Mol F. | : C22H28N3O9P |
| Mol W. | : 509.46 |
| Cat No. | : SA15411 |
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Description
| Product Name | 2′-Alkene Sofosbuvir; 2’-Defluro-2’-methylene Sofosbuvir |
| Synonyms | isopropyl ((S)-(((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methylenetetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate |
| Related API | Sofosbuvir |
| Category | Impurities |
2′-Alkene Sofosbuvir; 2’-Defluro-2’-methylene Sofosbuvir product with CAS: 2095551-20-3 is also known as isopropyl ((S)-(((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methylenetetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. It is used in Sofosbuvir impurity profiling as per limits and threshold values specified by respective drug legislation, FDA, and pharmacopoeial guidelines. Moreover, isopropyl ((S)-(((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methylenetetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.
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