Fosaprepitant Dimeglumine
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| CAS No. | : 265121-04-8 |
| Mol F. | : C37H56F7N6O16P (Dimeglumine salt) |
| Mol W. | : 1004.83 |
| Cat No. | : SA45425 |
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Description
| Product Name | (1R, 2R, 3S) Fosaprepitant Dimeglumine |
| Synonyms | [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol |
| Related API | Fosaprepitant |
| Category | Impurities |
(1R, 2R, 3S) Fosaprepitant Dimeglumine product with CAS: 265121-04-8 is also known as [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. It is used in Fosaprepitant impurity profiling as per limits and threshold values specified by respective drug legislation, FDA, and pharmacopoeial guidelines. Moreover, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.
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