Trazodone

Trazodone Impurities

Trazodone impurities include synthetic intermediates, degradation products, process-related compounds, and potential nitrosamine contaminants that may arise during synthesis, formulation, or storage. As a serotonin antagonist and reuptake inhibitor (SARI) used in the treatment of major depressive disorder, anxiety, and insomnia, impurity profiling is essential to ensure product safety, therapeutic efficacy, and regulatory compliance. All impurity compounds are structurally characterized and qualified under ICH guidelines for toxicological evaluation and analytical validation.

Trazodone EP Impurities

Pharmacopeial and non-pharmacopeial Trazodone impurity compounds are available in compliance with European Pharmacopoeia (EP) specifications. These standards support analytical method development, impurity profiling, and stability testing. EP traceable materials are supplied with validated analytical data including purity, structural confirmation, and spectral characterization.

Trazodone Related Compounds

Structurally related compounds and synthetic analogs associated with Trazodone are included for use in impurity identification, toxicological qualification, and regulatory submission. These materials are thoroughly characterized and conform to international standards. Related compounds are used in forced degradation studies, genotoxicity assessments, and impurity threshold evaluations.

Trazodone Impurity Reference Standards

Trazodone impurity reference standards are provided with validated analytical data including purity, NMR, MS, and full Certificates of Analysis. These standards are used in pharmaceutical research, method validation, and GMP-compliant quality control. EP/USP traceable entries are available upon request and are routinely re-tested to ensure consistency and reliability.