Sumatriptan is a serotonin receptor agonist used to treat migraines and cluster headaches. Sumatriptan is an agonist of 5-HT1B and 5-HT1D. This agonism leads to constriction of cranial blood vessels and inhibits the release of pro-inflammatory neuropeptides. Sumatriptan decreases carotid arterial blood flow, but increases blood flow velocity in the internal carotid artery and middle cerebral artery. Synthink is a most trusted source of Sumatriptan Degradation Impurity, Sumatriptan Genotoxic impurity, Sumatriptan Process Impurity, USP related compound, Sumatriptan Nitrosamine impurity, N-Nitroso impurity etc. which are listed on this page.