Spironolactone

Spironolactone is an aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, adrenal hyperplasia, heart failure, deem, hirsutism (off-label) and hypokalemia. Spironolactone is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. SynThink provides high purity Spironolactone impurities material, Spironolactone reference standards and usp related compounds including – Spironolactone Degradation Impurity, Spironolactone Process Impurity, Potential Impurity, Spironolactone Related Compounds, Spironolactone Metabolites. Spironolactone related compounds or impurity standards are used in the quality, stability, and toxicity study of Spironolactone products as well as HPLC method development/validation.