Ribociclib is an inhibitor of cyclin D1/Cyclin-dependent kinase 4(CDK4) and Cell division protein kinase 6 (CDK6). Ribociclib is used for the treatment of certain kinds of breast cancer. Ribociclib is a kinase inhibitor indicated in combination with an aromatase inhibitor which is used for the treatment of pre/perimenopausal or postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, as initial endocrine-based therapy. Various Ribociclib related compounds or reference standards, listed on this page are needed in pharmaceutical research at the time to product development, ANDA filing or during production to study quality, stability, and genotoxicity study of Ribociclib related products.
Synthink is a most trusted source of Ribociclib Degradation Impurities, Ribociclib Genotoxic impurity, Ribociclib Process Impurities, USP related compounds, Ribociclib Nitrosamine impurity, N-Nitroso impurity etc. which are listed on this page.
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Impurities, Ribociclib Impurities2,5-Dibromo-N-cyclopentylpyrimidin-4-amine
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CAS No. : 2481084-18-6 Mol F. : C9H11Br2N3 Mol W. : 321 Cat No. : SA47112 -
Impurities, Ribociclib Impurities(2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol
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CAS No. : 1374639-77-6 Mol F. : C12H14ClN3O Mol W. : 251.71 Cat No. : SA47124 -
Impurities, Ribociclib Impurities3-(2-Chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol
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CAS No. : 1374639-76-5 Mol F. : C12H14ClN3O Mol W. : 251.7 Cat No. : SA47123 -
Impurities, Ribociclib Impurities4-(4-(6-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid
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CAS No. : NA Mol F. : C27H34N8O4 Mol W. : 534.6 Cat No. : SA47122 -
Impurities, Ribociclib ImpuritiesRibociclib N,N-DiDesmethyl Metabolite
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CAS No. : NA Mol F. : C21H26N8O Mol W. : 406 Cat No. : SA47121 -
Impurities, Ribociclib Impurities1-(6-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide
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CAS No. : NA Mol F. : C23H30N8O2 Mol W. : 450.54 Cat No. : SA47120 -
Impurities, Ribociclib Impurities2-(7-Cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-5-(piperazin-1-yl)pyridine 1-oxide
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CAS No. : 2069953-39-3 Mol F. : C23H30N8O2 Mol W. : 450.55 Cat No. : SA47119 -
Impurities, Ribociclib Impurities7-cyclopentyl-6-(dimethylcarbamoyl)-2-(5-(piperazin-1-yl)pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine 7-oxide
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CAS No. : NA Mol F. : C23H30N8O2 Mol W. : 450.54 Cat No. : SA47118 -
Impurities, Ribociclib Impurities(E)-1,2-Bis(5-chloropyridin-2-yl)diazene 1-oxide
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CAS No. : NA Mol F. : C10H6Cl2N4O Mol W. : 269.1 Cat No. : SA47117 -
Impurities, Ribociclib Impurities3-(2-((3-(2-chloro-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-yl)oxy)-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol
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CAS No. : NA Mol F. : C24H27ClN6O2 Mol W. : 467 Cat No. : SA47116 -
Impurities, Ribociclib Impurities3,3′-(4-(Cyclopentylamino)pyrimidine-2,5-diyl)bis(prop-2-yn-1-ol)
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CAS No. : NA Mol F. : C15H17N3O2 Mol W. : 271.3 Cat No. : SA47115 -
Impurities, Ribociclib Impurities3-(2-((2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methoxy)-4-(cyclopentylamino)pyrimidin-5-yl)prop-2-yn-1-ol
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CAS No. : NA Mol F. : C24H27ClN6O2 Mol W. : 467 Cat No. : SA47114 -
Impurities, Ribociclib Impurities2-((2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methoxy)-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C26H30ClN7O2 Mol W. : 508 Cat No. : SA47113 -
Impurities, Ribociclib Impurities7-cyclopentyl-2-((3,6-dihydroxy-5-(piperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2, 3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C23H30N8O3 Mol W. : 466.55 Cat No. : SA47100 -
Impurities, Ribociclib Impurities2,5-Dichloro-N-cyclopentylpyrimidin-4-amine
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CAS No. : 1214279-37-4 Mol F. : C9H11Cl2N3 Mol W. : 232.1 Cat No. : SA47111 -
Impurities, Ribociclib Impurities5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine
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CAS No. : 1823404-28-9 Mol F. : C9H11BrClN3 Mol W. : 276.56 Cat No. : SA47010 -
Impurities, Ribociclib Impurities7-Cyclopentyl-N,N-dimethyl-2-(nitroso(5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C23H28N10O3 Mol W. : 492.5 Cat No. : SA47109 -
Impurities, Ribociclib Impurities7-Cyclopentyl-N,N-dimethyl-2-(nitroso(5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C23H29N9O2 Mol W. : 463.5 Cat No. : SA47108 -
Impurities, Ribociclib ImpuritiesMethyl 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate
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CAS No. : NA Mol F. : C22H27N7O2 Mol W. : 421.51 Cat No. : SA47107 -
Impurities, Ribociclib Impurities7-cyclopentyl-2-((5-((2-formamidoethyl)amino)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C22H28N8O2 Mol W. : 436.52 Cat No. : SA47106 -
Impurities, Ribociclib Impurities7-cyclopentyl-2-((5-(4-formylpiperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C24H30N8O2 Mol W. : 462.56 Cat No. : SA47105 -
Impurities, Ribociclib ImpuritiesN-Desmethyl Ribociclib
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CAS No. : 1211441-59-6 Mol F. : C22H28N8O Mol W. : 420.52 Cat No. : SA47104 -
Impurities, Ribociclib Impurities7-cyclopentyl-2-((3-hydroxy-5-(piperazin-1-yl)pyridin-2-yl)amino)-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C23H30N8O2 Mol W. : 450.55 Cat No. : SA47103 -
Impurities, Ribociclib Impurities7-cyclopentyl-N-(hydroxymethyl)-N-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-p yrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : NA Mol F. : C23H30N8O2 Mol W. : 450.55 Cat No. : SA47102 -
Impurities, Ribociclib Impurities2-((5-((2-Aminoethyl)amino)pyridin-2-yl)amino)-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
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CAS No. : 2460738-27-4 Mol F. : C21H28N8O Mol W. : 408.5 Cat No. : SA47101
