Tofacitinib Related Compound 11

Tofacitinib Related Compound 11 product with CAS: 1640971-60-3 is also known as 3-((3R,4R)-3-((6-Aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile. This product can be used as a working standard or secondary reference standard. Additional internal validation as per respective FDA regulations/guidelines may require. Tofacitinib Related Compound 11 is generally used for Quality Control (QC), Quality Assurance (QA) during commercial production of Tofacitinib and its related formulations. Moreover, 3-((3R,4R)-3-((6-Aminopyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation.