11-Keto Loteprednol etabonate product with CAS: 207670-54-0 is also known as (10R,13S,17R)-chloromethyl 17-(ethoxycarbonyloxy)-10,13-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate; (8S,9S,10R,13S,14S,17R)-Chloromethyl 17-((Ethoxycarbonyl)oxy)-10,13-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate. This product can be used as a working standard or secondary reference standard (additional internal validation as per respective FDA regulations/guidelines may require). 11-Keto Loteprednol etabonate is used in Loteprednol impurity profiling as per limits and threshold values specified by respective drug legislation, FDA, and pharmacopoeial guidelines during commercial production of Loteprednol and its related formulations. Moreover, (10R,13S,17R)-chloromethyl 17-(ethoxycarbonyloxy)-10,13-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate is also used in the process of Abbreviated New Drug Application (ANDA) filing to FDA and toxicity study of respective drug formulation. Please also find out other impurities of Loteprednol developed in our R&D.
